The Greensboro Zoning Commission hears and decides requests for amendments to the City's official Zoning Map. The duties of the commission include hearing requests to rezone properties, including conditional zoning districts, reviewing original zoning requests (associated with annexations), reviewing requests for Special Use Permits, and reviewing and recommending boundaries for new or altered zoning overlay districts.

The Zoning Commission is composed of nine citizen members appointed by City Council for three-year terms. Regular meetings are held on the third Monday of each month